Search on: NARC-1 PROTEIN 
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Descriptor English:   Proprotein Convertase 9 
Descriptor Spanish:   Proproteína Convertasa 9 
Descriptor Portuguese:   Pró-Proteína Convertase 9 
Synonyms English:   NARC-1 Protein
Neural Apoptosis-Regulated Convertase 1
Proprotein Convertase, Subtilisin-Kexin Type 9
Convertase 9, Proprotein
NARC 1 Protein
Neural Apoptosis Regulated Convertase 1
Proprotein Convertase, Subtilisin Kexin Type 9  
Tree Number:   D08.811.277.656.300.760.718
D08.811.277.656.837.688
D08.811.277.656.959.350.718
Definition English:   A proprotein convertase that is essential for CHOLESTEROL homeostasis. It binds to and is required for the lysosomal degradation of the LDL RECEPTOR (LDLR); the VLDL receptor, and the APOLIPOPROTEIN E RECEPTOR. It also regulates neuronal APOPTOSIS. 
History Note English:   2017 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56481 
Unique Identifier:   D000071449 

Occurrence in VHL:
 

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